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EtOH up to 20 mM
2 h for mouse (3
Chemical Name: N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-[(furan-2-yl)methyl]methanesulfonamide
PI-103 inhibits constitutive and growth factor-induced PI3K/Akt
It activates human TRPA1 via photochemical reactions with redox-sensitive cysteine residues (EC50 ~2 µM)
Rosuvastatin Calcium 60107 EtOH up to 20 mMRosuvastatin Calcium (Rosuvastatin hemicalcium) is a competitive HMG CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks human ether a go go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock